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Its never fooly explained however, it took multiple wolves (La Push Shapeshifters) to kill Laurent, and Caius servived an (real) wolf attack.

a vampire can be more powerful than shapeshifter if he or she has a very special offensive ability like jane's illusion of pain or alec's sensory paralysys or Jaspers ability to toy with peoples emotions . but if the vampire has no special gift the shapeshifter is much stronger

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